We aim to apply fundamental discoveries in materials science to improve medical care throughout the world by translating research into tangible technologies with societal and clinical impact. One major challenge is the global supply chain for vaccines and emerging biologics, which currently depends on a costly and burdensome cold chain. Therefore, we have been developing options to use polymeric materials for thermal stabilization of complex biomolecules. Based on these findings, Nanoly Bioscience (www.nanoly.info) is utilizing a nanoscale polymer solution (NanoShield) to thermally-stabilize vaccines with the aim of mitigating cold chain requirements during shipment to the developing world. Nanoly has been recognized with Intel's Top Social Innovation, Dell's Global Social Innovation Challenge Winner, 2014 Tech Awards Katherine M. Swanson Young Innovator Award, and Materials and Manufacturing Award by Airbus at Hello Tomorrow Conference 2015.
Tibbitt, M.W.; Han, B.W.; Kloxin, A.M.; Anseth, K.S. "Synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery" Journal of Biomedical Materials Research Part A, 2012, 100, 1647-1654. (Award article)
Appel, E.A.*; Tibbitt, M.W.*; Webber, M.J.; Mattix, B.A.; Veiseh, O.; Langer, R. "Self-assembled hydrogels utilizing polymer-nanoparticle interactions" Nature Communications, 2015, 6, 6295.