Journal Articles

Fenton, O.S.; Kauffman, K.J.; Kaczmarek, J.C.; McClellan, R.L.; Jhunjhunwala, S.; Tibbitt, M.W.; Zeng, M.D.; Appel, E.A.; Dorkin, J.R.; Mir, F.F.; Yang, J.H.; Oberli, M.A.; Heartlein, M.W.; DeRosa, F.; Langer, R.; Anderson, D.G. "Synthesis and biological evaluation of ionizable lipid materials for the in vivo delivery of messenger RNA to B lymphocytes" Advanced Materials, Accepted.

Tibbitt, M.W.; Langer, R. "Living biomaterials" Accounts of Chemical Research2017, 50, 508-513.

Detappe, A.; Thomas, E.; Tibbitt, M.W.; Kunjachan, S.; Zavidij, O.; Parnandi, N.; Reznichenko, E.; Lux, F.; Tillement, O.; Berbeco, R. "Ultrasmall silica-based bismuth gadolinium nanoparticles for dual magnetic resonance-computed tomography image guided radiation therapyNano Letters2017, 17, 1733-1740.

van der Ven, C.F.T.; Wu, P.J.; Tibbitt, M.W.; van Mil, A.; Sluijter, J.P.G.; Langer, R.; Aikawa, E. "In vitro 3D model and miRNA drug delivery to target calcific aortic valve diseaseClinical Science2017131, 181-195.

Yu, A.C.; Chen, H.; Chan, D.; Agmon, G.; Stapleton, L.M.; Sevit, A.M.; Tibbitt, M.W.; Acosta, J.D.; Zhang, T.; Franzia, P.W.; Langer, R.; Appel, E.A. "Scalable manufacturing of biomimetic moldable hydrogels for industrial applicationsProceedings of the National Academy of Sciences2016113, 14255-14260.

Fenton, O.S.; Kauffman, K.J.; McClellan, R.L.; Appel, E.A.; Dorkin, J.R. ; Tibbitt, M.W.; Heartlein, M.W.; DeRosa, F.; Langer, R.; Anderson, D.G. "Bioinspired alkenyl amino alcohol ionizable lipid materials for highly potent in vivo mRNA deliveryAdvanced Materials2016, 28, 2939-2943.

Patel, A.K.; Tibbitt, M.W.; Celiz, A.D.; Davies, M.C.; Langer, R.; Denning, C.; Alexander, M.R.; Anderson, D.G. "High throughput screening for discovery of materials that control stem cell fateCurrent Opinion in Solid State and Materials Science2016, 20, 202-211.

Tibbitt, M.W.; Dahlman, J.E.; Langer, R. "Emerging frontiers in drug deliveryJournal of the American Chemical Society2016, 138, 704-717.

Tibbitt, M.W.*; Rodell, C.B.*; Burdick, J.A.; Anseth, K.S. "Progress in material design for biomedical applications" Proceedings of the National Academy of Sciences2015, 112, 14444-14451.

Appel, E.A.; Tibbitt, M.W.; Greer, J.M.; Fenton, O.S.; Kreuls, K.; Anderson, D.G.; Langer, R. "Exploiting Electrostatic Interactions in Polymer-Nanoparticle HydrogelsACS Macro Letters20154, 848-852.

Lewis, K.J.R.; Tibbitt, M.W.; Zhao, Y.; Branchfield, K.; Sun, X.; Balasubramaniam, V.; Anseth, K.S. "In vitro model alveoli from photodegradable microspheresBiomaterials Science20153, 821-832. (Front cover)

Appel, E.A.*Tibbitt, M.W.*; Webber, M.J.; Mattix, B.A.; Veiseh, O.; Langer, R. "Self-assembled hydrogels utilizing polymer-nanoparticle interactionsNature Communications2015, 6, 6295.

Yang, C.*; Tibbitt, M.W.*; Basta, L.; Anseth, K.S. "Reversible and irreversible effects of mechanical dosing on stem cell fateNature Materials201413, 645-652.

Wang, H.; Tibbitt, M.W.; Langer, S.J.; Leinwand, L.A.; Anseth, K.S. "Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathwayProceedings of the National Academy of Sciences2013110, 19336-19341.

Tibbitt, M.W.; Kloxin, A.M.; Sawicki, L.A.; Anseth, K.S. "Mechanical properties and degradation of chain and step-polymerized photodegradable hydrogelsMacromolecules201346, 2785-2792.

Shenoy, R.; Tibbitt, M.W.; Anseth, K.S.; Bowman, C.N. "Formation of core-shell particles by interfacial radical polymerization initiated by a glucose oxidase-mediated redox systemChemistry of Materials201325, 761-767.

Tibbitt, M.W.; Kloxin, A.M.; Anseth, K.S. "Modeling controlled photodegradation in optically thick hydrogelsJournal of Polymer Science Part A: Polymer Chemistry201351, 1899-1911.

Tibbitt, M.W.; Anseth, K.S. "Dynamic microenvironments: the fourth dimensionScience Translational Medicine20124, 160ps24. (Front cover)

Kloxin, A.M.; Lewis, K.J.R.; DeForest, C.A.; Seedorf, G.; Tibbitt, M.W.; Balasubramaniam, V.; Anseth, K.S. "Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3DIntegrative Biology20124, 1540-1549.

Guo, Q.; Wang, X.; Tibbitt, M.W.; Anseth, K.S.; Montell, D.J.; Elisseeff, J.H. "Light activated cell migration in synthetic extracellular matricesBiomaterials201233, 8040-8046.

Azagarsamy, M.A.; Alge, D.L.; Radhakrishnan, S.J.; Tibbitt, M.W.; Anseth, K.S. "Photocontrolled nanoparticles for on-demand release of proteinsBiomacromolecules201213, 2219-2224.

Tibbitt, M.W.; Han, B.W.; Kloxin, A.M.; Anseth, K.S. "Synthesis and application of photodegradable microspheres for spatiotemporal control of protein deliveryJournal of Biomedical Materials Research Part A2012100, 1647-1654. (Award article)

Kloxin, A.M.; Tibbitt, M.W.; Anseth, K.S. "Synthesis of photodegradable hydrogels as dynamically tunable cell culture platformsNature Protocols20105, 1867-1887.

Tibbitt, M.W.; Kloxin, A.M.; Dyamenahalli, K.U.; Anseth, K.S. "Controlled two-photon photodegradation of PEG hydrogels to study and manipulate subcellular interactions on soft materialsSoft Matter20106, 5100-5108.

Kloxin, A.M.; Tibbitt, M.W.; Kasko, A.M.; Fairbairn, J.A.; Anseth, K.S. "Tunable hydrogels for external manipulation of cellular microenvironments through controlled photodegradationAdvanced Materials201022, 61-66.

Tibbitt, M.W.; Anseth, K.S. "Hydrogels as extracellular matrix mimics for 3D cell cultureBiotechnology and Bioengineering2009103, 655-663.

Aimetti, A.A.; Tibbitt, M.W.; Anseth, K.S. "Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogelsBiomacromolecules200910, 1484-1489.


Book Chapters

Tibbitt, M.W.; Shadish, J.; DeForest, C.A. "Photopolymers for multiphoton lithography in biomaterials and hydrogels" Multiphoton Lithography: Techniques, Materials, and Applications. Ed. Stampfl, J.; Liska, R.; Ovsianikov, A. Weinham, Germany: Wiley-VCH Verlag GmbH & Co., 2017. 183-220. Print.



Appel, E.A.; Tibbitt, M.W.; Langer, R. "Biodegradable shear-thinning injectable hydrogels" Submitted.

Tibbitt, M.W.; Anseth, K.S.; Kloxin, A.M.; Toner, M.; Oakey, J.; Shah, A. "Selective capture and release of rare mammalian cells using photodegradable hydrogels in a microfluidic platform" WO2015010019A1, US20160153999.

Anseth, K.S.; Kasko, A.M.; Tibbitt, M.W.; Kloxin, A.M.; Sridhar, B. "Photodegradable groups for tunable polymeric materials" US9180196.